Veuillez utiliser cette adresse pour citer ce document : http://imsear.hellis.org/handle/123456789/183438
Titre: Danazol-induced Acute Pulmonary Fibrosis in a Patient with Idiopathic Thrombocytopenic Purpura: Could Anti Fibrosant Therapy be Useful?.
Auteur(s): Flores-Franco, René Agustín
Salgado-Yáñez, Víctor Alejandro
Rivera-Olivas, Jesús
Ramos-Martínez, Ernesto
Mots-clés: Idiopathic thrombocytopenic purpura
danazol
lung fibrosis
N-acetylcysteine
pirfenidone.
Date de publication: 2016
Référence bibliographique: Flores-Franco René Agustín, Salgado-Yáñez Víctor Alejandro, Rivera-Olivas Jesús, Ramos-Martínez Ernesto. Danazol-induced Acute Pulmonary Fibrosis in a Patient with Idiopathic Thrombocytopenic Purpura: Could Anti Fibrosant Therapy be Useful?. British Journal of Medicine and Medical Research. 2016; 16(12):1-4.
Résumé: Introduction: Danazol is frequently used in the treatment of idiopathic thrombocytopenic purpura (ITP). Very occasionally are described in the elderly fatal respiratory complications related to this drug such as acute pulmonary fibrosis for which no treatment has proven to be effective. Presentation of Case: We describe a case of an old man with ITP treated with danazol who developed a pulmonary fibrosing disease not attributed to any other cause. Damaged lung reversed using an anti fibrosant therapy approved for other types of pulmonary fibrosing diseases. Discussion and Conclusion: Pulmonary fibrosing disease attributed to danazol is a condition refractory to systemic corticosteroids, but as shown in the present case, an anti fibrosant therapy has proven to be a useful alternative and could be recommended in the light of current knowledge.
URI/URL: http://imsear.hellis.org/handle/123456789/183438
ISSN: 2231-0614
Collection(s) :British Journal of Medicine and Medical Research

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