Please use this identifier to cite or link to this item:
|Title:||Anti-Helminthic Potential of Solvent Extracts of Indigenous Botanicals.|
|Citation:||Jain Rashmi, Shubham, Ansari Shabista, Aswal Deepali, Mathur Abhishek. Anti-Helminthic Potential of Solvent Extracts of Indigenous Botanicals. International Journal of Applied Biology and Pharmaceutical Technology. 2015 Oct-Dec; 6(4): 102-105.|
|Abstract:||Ethno botanical studies reveal that the indigenous knowledge of a community is a key player in the identification of medicinal plants and such plants have been often tested by generations of indigenous people. In the present investigation, the hydro-alcoholic extracts of leaves of Azadirachta indica (Neem) and Swertia chirayta (Chirayta) were assessed for anti-helminthic potential against helminths (earthworms were used as model) at 10, 50 and 100 mg/ml. No anti-helminthic potential was observed at 10 mg/ml of dose of the hydro-alcoholic extracts of Swertia chirayta. The hydro-alcoholic extracts of both the plants showed significant anti-helminthic activity on selected worms at higher doses. Hydro-alcoholic leaves extracts of Azadirachta indica (Neem) was found to be more active as compared to hydro-alcoholic whole plant extracts of Swertia chirayta (Chirayta) at concentration of 100 mg/ml. It was observed that with the variation in dose, the death time and paralysis time of the worms’ decreases. The results indicated that extracts possessed dose dependent anti-helminthic activity. The results were compared to Piperazine citrate and Albendazole (15 mg/ml). The hydro-alcoholic extracts demonstrated paralysis as well as death of worms in a less time in comparison to the standard drugs. The anti-helminthic activity of the extracts indicates the presence of active principle responsible for anti-helminthic activity.|
|Appears in Collections:||International Journal of Applied Biology and Pharmaceutical Technology|
Files in This Item:
|ijabpt2015v6n4p102.pdf||Research article||408.16 kB||Adobe PDF|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.