Please use this identifier to cite or link to this item: http://imsear.hellis.org/handle/123456789/169092
Title: Phytochemical and Antidepressant Activities of Selaginella Bryopteris (L.) Baker on Albino Mice.
Authors: Chandrakant, Jyothi
Mathad, Pratima
Mety, Sundar
Ahmed, MD Liyakat
Sanaullah, MD
Keywords: Antidepressant
Depression
Hole board test
Rotarod test
Selaginella bryopteris
Issue Date: Oct-2015
Citation: Chandrakant Jyothi, Mathad Pratima, Mety Sundar, Ahmed MD Liyakat, Sanaullah MD. Phytochemical and Antidepressant Activities of Selaginella Bryopteris (L.) Baker on Albino Mice. International Journal of Applied Biology and Pharmaceutical Technology. 2015 Oct-Dec; 6(4): 14-19.
Abstract: Selaginella bryopteris is a pteridophytic plant belongs to the family selaginellaceae. Its familiar name is sanjeevani booti. The present study emphasized on phytochemical screening and antidepressant activity of Selaginella bryopteris on Albino mice. Phytochemical analysis was carried with a view to asses the therapeutic values and safty of plant in ethnomedicine. The results of the phytochemical screening shows the presence of alkaloids, flavonoids, phenols, tannins and results of the quantitative estimations revealed that maximum amount of alkaloids are present in methanolic extract when compared to flavonoids, phenols and tannins. From the results of the phytochemical estimations methanolic extract is found to be efficient. The antidepressant activity of Selaginella bryopteris was tested on mice by Hole board test and Rotarod test. In both the tests Diazepam (depressant/ for inducing depressant) is used as standard. The results of the Hole board test showed significant motar performance (head dipping behavior) with the dose of 250mg/kg (48.66±4.05 at 120min) and 500mg/kg ( 69.33±6.36 at 120min) compared to standard of 10mg/kg (1.66±1.20 at 120min) and it was very interesting to note that retention time of mice has been significantly improved in Rotarod test with the dose of 250mg/kg (3.96±0.35) and 500mg/kg (7.23±0.46) of the methanolic extract of Selaginella bryopteris.
URI: http://imsear.hellis.org/handle/123456789/169092
ISSN: 0976-4550
Appears in Collections:International Journal of Applied Biology and Pharmaceutical Technology

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